Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phosphorylation of linker histone H1 regulates gene expression in vivo by mimicking H1 removal.

Molecular cell - 1 Oct 1999

Dou Y, Mizzen C A, Abrams M, Allis C D, Gorovsky M A

Abstract excerpt

Two Tetrahymena strains were created by gene replacement. One contained H1 with all phosphorylation sites mutated to alanine, preventing phosphorylation. The other had these sites changed to glutamic acid, mimicking the fully phosphorylated state. Global gene expression was not detectably changed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Genetically Modified
Share to Genes, Protozoan
Share to Histones

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutagenesis, Site-Directed

Share to Phosphorylation

Share to Protozoan Proteins

Share to Tetrahymena thermophila

Share to Transformation, Genetic

Source

Identifiers

PMID: 10549296
DOI: 10.1016/s1097-2765(00)80215-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-10549296-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phosphorylation of linker histone H1 regulates gene expression in vivo by mimicking H1 removal.PMID 10549296Read ↗

Phosphorylation and an ATP-dependent process increase the dynamic exchange of H1 in chromatin.Semantic proximity Read ↗

A genetic analysis reveals novel histone residues required for transcriptional reprogramming upon stress.Semantic proximity Read ↗

Regulation of transcription by H1 phosphorylation in Tetrahymena is position independent and requires clustered sites.Semantic proximity Read ↗

Expression of Tetrahymena histone H4 in yeast.Semantic proximity Read ↗

Decreased expression of specific genes in yeast cells lacking histone H1.Semantic proximity Read ↗

Suppression of histone H1 genes in Arabidopsis results in heritable developmental defects and stochastic changes in DNA methylation.Semantic proximity Read ↗

Evolution of protein phosphorylation across 18 fungal species.Semantic proximity Read ↗

Linker Histone H1.2 cooperates with Cul4A and PAF1 to drive H4K31 ubiquitylation-mediated transactivation.Semantic proximity Read ↗

Functional connection between histone acetyltransferase Gcn5p and methyltransferase Hmt1p.Semantic proximity Read ↗

Histone H1 diversity: bridging regulatory signals to linker histone function.Semantic proximity Read ↗

RETRACTED: TAF1 activates transcription by phosphorylation of serine 33 in histone H2B.Semantic proximity Read ↗

Identification and mutation of phosphorylation sites in a linker histone. Phosphorylation of macronuclear H1 is not essential for viability in tetrahymena.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.