Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Histone H2A.Z has a conserved function that is distinct from that of the major H2A sequence variants.

Nucleic acids research - 1 Oct 2000

Jackson J D, Gorovsky M A

Abstract excerpt

Saccharomyces cerevisiae contains three genes that encode members of the histone H2A gene family. The last of these to be discovered, HTZ1 (also known as HTA3), encodes a member of the highly conserved H2A.Z class of histones. Little is known about how its in vivo function compares with that of the better studied genes (HTA1 and HTA2) encoding the two major H2As. We show here that, while the HTZ1 gene encoding...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Conserved Sequence
Share to Gene Expression Regulation, Fungal
Share to Genes, Essential

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Fungal

Share to Genes, Protozoan

Share to Genetic Complementation Test

Share to Histones

Share to Tetrahymena thermophila

Source

Open in PubMed Open full text

Identifiers

PMID: 11000274
DOI: 10.1093/nar/28.19.3811
PMCID: PMC110762

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Histone H2A.Z has a conserved function that is distinct from that of the major H2A sequence variants.PMID 11000274Read ↗

Either of the major H2A genes but not an evolutionarily conserved H2A.F/Z variant of Tetrahymena thermophila can function as the sole H2A gene in the yeast Saccharomyces cerevisiae.Semantic proximity Read ↗

Global analysis for functional residues of histone variant Htz1 using the comprehensive point mutant library.Semantic proximity Read ↗

H2A.Z functions to regulate progression through the cell cycle.Semantic proximity Read ↗

The nonessential H2A N-terminal tail can function as an essential charge patch on the H2A.Z variant N-terminal tail.Semantic proximity Read ↗

What makes a histone variant a variant: Changing H2A to become H2A.Z.Semantic proximity Read ↗

Replacement of Arabidopsis H2A.Z with human H2A.Z orthologs reveals extensive functional conservation and limited importance of the N-terminal tail sequence for Arabidopsis developmentSemantic proximity Read ↗

[H2A.Z: a histone variant that decorates gene promoters].Semantic proximity Read ↗

Key functional regions in the histone variant H2A.Z C-terminal docking domain.Semantic proximity Read ↗

Individual lysine acetylations on the N terminus of Saccharomyces cerevisiae H2A.Z are highly but not differentially regulated.Semantic proximity Read ↗

Single residue changes to the histone core catalyze neofunctionalization and impose fitness trade-offsSemantic proximity Read ↗

Phosphorylation of the SQ H2A.X motif is required for proper meiosis and mitosis in Tetrahymena thermophila.Semantic proximity Read ↗

Non-redundant functions of H2A.Z.1 and H2A.Z.2 in chromosome segregation and cell cycle progressionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.