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Article

A preS mutation isolated from a patient with chronic hepatitis B infection leads to virus retention and misassembly.

Gastroenterology - 1 Dec 1997

Bock C T, Tillmann H L, Maschek H J, Manns M P, Trautwein C

Abstract excerpt

A preS mutation derived from a patient with chronic hepatitis B virus (HBV) infection who had HBV reinfection with fibrosing cholestatic hepatitis after orthotopic liver transplantation was characterized. Sequence analysis of the HBV genome revealed two deletions and a point mutation in the regulatory CCAAT element of the S promoter. To investigate the particular preS mutation for replication competence and viral...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9394738
DOI: 10.1016/s0016-5085(97)70018-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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