Article
Impact of hepatitis B virus (HBV) preS/S genomic variability on HBV surface antigen and HBV DNA serum levels.
Hepatology (Baltimore, Md.) - 1 Aug 2012
Pollicino Teresa, Amaddeo Giuliana, Restuccia Agnese, Raffa Giuseppina, Alibrandi Angela, Cutroneo Giuseppina, Favaloro Angelo, Maimone Sergio, Squadrito Giovanni, Raimondo Giovanni
Abstract excerpt
UNLABELLED: To evaluate whether hepatitis B virus (HBV) preS/S gene variability has any impact on serum hepatitis B surface antigen (HBsAg) levels and to analyze the replication capacity of naturally occurring preS/S variants, sera from 40 untreated patients with HBV-related chronic liver disease (hepatitis B e antigen [HBeAg]-positive, n = 11; HBeAg-negative, n = 29) were virologically characterized....
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