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Article

Hepatitis B virus PreS/S gene variants: pathobiology and clinical implications.

Journal of hepatology - 1 Aug 2014

Pollicino Teresa, Cacciola Irene, Saffioti Francesca, Raimondo Giovanni

Abstract excerpt

The emergence and takeover of hepatitis B virus (HBV) variants carrying mutation(s) in the preS/S genomic region is a fairly frequent event that may occur spontaneously or may be the consequence of immunoprophylaxis or antiviral treatments. Selection of preS/S mutants may have relevant pathobiological and clinical implications. Both experimental data and studies in humans show that several specific mutations in...

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Identifiers

PMID: 24801416
DOI: 10.1016/j.jhep.2014.04.041

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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