Article
Hepatitis B virus mutations in the pre-S genome before and after liver transplantation.
Hepatology (Baltimore, Md.) - 1 Sept 1996
Trautwein C, Schrem H, Tillmann H L, Kubicka S, Walker D, Böker K H, Maschek H J, Pichlmayr R, Manns M P
Abstract excerpt
Mutational changes in the pre-S region of hepatitis B virus (HBV) were analyzed in 20 patients who experienced HBV reinfection after orthotopic liver transplantation (OLT). HBV DNA was extracted from patient sera before and after OLT. The pre-S sequence was amplified via polymerase chain reaction...
Topics
- Adult
- Base Sequence
- Female
- Genome, Viral
- Hepatitis B virus
- Humans
- Liver
- Liver Transplantation
- Male
- Middle Aged
- Molecular Probes
- Molecular Sequence Data
- Mutation
- Point Mutation
- Postoperative Period
- Recurrence
- Transcription, Genetic