Article
Structural organization of the synaptic exocytosis core complex.
Neuron - 1 Nov 1997
Lin R C, Scheller R H
Abstract excerpt
Syntaxin, vesicle-associated membrane protein (VAMP), and synaptosome-associated protein of 25 kDa (SNAP-25) form a ternary "core complex" central to the process of synaptic vesicle docking and fusion. Several lines of evidence support the hypothesis that the proteins assemble in a coiled-coil structure, but the alignment of alpha helices in this coil and the overall conformation of the coil are unknown. We...
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