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Article

Mutation and expression of the DCC gene in human lung cancer.

Neoplasia (New York, N.Y.) - 1 Jan 2000

Kohno T, Sato T, Takakura S, Takei K, Inoue K, Nishioka M, Yokota J

Abstract excerpt

Chromosome 18q is frequently deleted in lung cancers, and a common region of 18q deletions was mapped to chromosome 18q21. Since the DCC candidate tumor suppressor gene has been mapped in this region, mutation and expression of the DCC gene were examined in 46 lung cancer cell lines, consisting of 14 small cell lung carcinomas (SCLCs) and 32 non-small cell lung carcinomas (NSCLCs), to elucidate the pathogenetic...

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Share to Carcinoma, Small Cell
Share to Cell Adhesion Molecules
Share to DCC Receptor

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, DCC

Share to Polymorphism, Single-Stranded Conformational

Share to Receptors, Cell Surface

Share to Tumor Cells, Cultured

Share to Tumor Suppressor Proteins

Source

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Identifiers

PMID: 11005564
DOI: 10.1038/sj.neo.7900094
PMCID: PMC1550293

Genes

DCC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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