Concordant p53 and DCC alterations and allelic losses on chromosomes 13q and 14q associated with liver metastases of colorectal carcinoma.

doi:10.1002/ijc.2910530307

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Article

Concordant p53 and DCC alterations and allelic losses on chromosomes 13q and 14q associated with liver metastases of colorectal carcinoma.

International journal of cancer - 1 Feb 1993

Ookawa K, Sakamoto M, Hirohashi S, Yoshida Y, Sugimura T, Terada M, Yokota J

Abstract excerpt

To identify genetic alterations associated with acquisition of metastatic ability in colorectal carcinoma, 31 liver metastases and 40 primary tumors of colorectal carcinoma from 55 patients were analyzed for loss of chromosomal heterozygosity using 46 polymorphic DNA markers covering 15 chromosom...

Topics

Alleles
Chromosomes, Human, Pair 13
Chromosomes, Human, Pair 14
Colorectal Neoplasms
DNA, Neoplasm
Genes, DCC
Genes, p53
Humans
Liver Neoplasms
Polymorphism, Restriction Fragment Length
Sequence Deletion
Tumor Suppressor Protein p53

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Identifiers

PMID: 8094072
DOI: 10.1002/ijc.2910530307

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8094072-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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