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Article

Apolipoprotein E-associated risk for Alzheimer's disease in the African-American population is genotype dependent.

Annals of neurology - 1 Oct 1997

Sahota A, Yang M, Gao S, Hui S L, Baiyewu O, Gureje O, Oluwole S, Ogunniyi A, Hall K S, Hendrie H C

Abstract excerpt

As a part of our ongoing study on Alzheimer's disease (AD) in elderly African Americans, we obtained clinical assessment and apolipoprotein E (ApoE) genotype data on 288 individuals (including 60 with AD). The ApoE epsilon4 allele frequency was significantly increased in AD patients compared with controls. The age-adjusted odds ratio (OR) for AD in epsilon4 homozygotes was 4.83 (95% confidence interval [CI],...

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Source

Identifiers

PMID: 9382479
DOI: 10.1002/ana.410420418

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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