Article
Apolipoprotein E-associated risk for Alzheimer's disease in the African-American population is genotype dependent.
Annals of neurology - 1 Oct 1997
Sahota A, Yang M, Gao S, Hui S L, Baiyewu O, Gureje O, Oluwole S, Ogunniyi A, Hall K S, Hendrie H C
Abstract excerpt
As a part of our ongoing study on Alzheimer's disease (AD) in elderly African Americans, we obtained clinical assessment and apolipoprotein E (ApoE) genotype data on 288 individuals (including 60 with AD). The ApoE epsilon4 allele frequency was significantly increased in AD patients compared with...
Topics
- Aged
- Alzheimer Disease
- Apolipoproteins E
- Black People
- Female
- Genotype
- Humans
- Incidence
- Male
- Prevalence
- Risk Factors
- United States
- Black or African American