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Apolipoprotein E and Alzheimer's disease pathology in African American older adults.

Neurobiology of aging - 1 Jul 2024

Royse Sarah K, Snitz Beth E, Hill Ashley V, Reese Alexandria C, Roush Rebecca E, Kamboh M Ilyas, Bertolet Marnie, Saeed Anum, Lopresti Brian J, Villemagne Victor L, Lopez Oscar L, Reis Steven E, Becker James T, Cohen Ann D

Abstract excerpt

The apolipoprotein-E4 (APOE*4) and apolipoprotein-E2 (APOE*2) alleles are more common in African American versus non-Hispanic white populations, but relationships of both alleles with Alzheimer's disease (AD) pathology among African American individuals are unclear. We measured APOE allele and β-amyloid (Aβ) and tau using blood samples and positron emission tomography (PET) images, respectively. Individual...

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PMID: 38582070
DOI: 10.1016/j.neurobiolaging.2024.03.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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