Article
Influence of APOE genotype on familial aggregation of AD in an urban population.
Neurology - 11 Sept 1999
Devi G, Ottman R, Tang M, Marder K, Stern Y, Tycko B, Mayeux R
Abstract excerpt
OBJECTIVE: To examine the influence of the proband's APOE genotype on AD among first-degree relatives in a community-based study of African Americans, whites, and Caribbean Hispanics. METHODS: History of AD and demographic information were obtained on 1,073 siblings and parents of 312 patients with AD and 2,722 siblings and parents of 802 nondemented controls. APOE genotyping was performed on all 1,114 patients...
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