Article
The APOE-epsilon4 allele and the risk of Alzheimer disease among African Americans, whites, and Hispanics.
JAMA - 11 Mar 1998
Tang M X, Stern Y, Marder K, Bell K, Gurland B, Lantigua R, Andrews H, Feng L, Tycko B, Mayeux R
Abstract excerpt
CONTEXT: Although the association between Alzheimer disease (AD) and the apolipoprotein E epsilon4 (APOE-epsilon4) allele has been confirmed worldwide, it appears to be inconsistent among African Americans, Hispanics, and Nigerians. OBJECTIVE: To investigate the association between the APOE-epsil...
Topics
- Aged
- Aged, 80 and over
- Alleles
- Alzheimer Disease
- Apolipoproteins E
- Black People
- Female
- Gene Frequency
- Hispanic or Latino
- Humans
- Longitudinal Studies
- Male
- Proportional Hazards Models
- Prospective Studies
- Risk Factors
- White People
- Black or African American