Article
Association between apolipoprotein E genotype and Alzheimer disease in African American subjects.
Archives of neurology - 1 Apr 2002
Graff-Radford Neill R, Green Robert C, Go Rodney C P, Hutton Michael L, Edeki Timi, Bachman David, Adamson Jennifer L, Griffith Patrick, Willis Floyd B, Williams Mary, Hipps Yvonne, Haines Jonathan L, Cupples L Adrienne, Farrer Lindsay A
Abstract excerpt
BACKGROUND: The association between Alzheimer disease (AD) and genotypes at the apolipoprotein E (APOE) locus has been confirmed in numerous populations worldwide, but appears to be inconsistent in African American subjects. OBJECTIVE: To investigate the association between APOE genotypes and AD in elderly African American subjects. DESIGN: Clinic-based, multicenter case-control study and a family study....
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