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Article

Serum cholesterol, APOE genotype, and the risk of Alzheimer's disease: a population-based study of African Americans.

Neurology - 11 Jan 2000

Evans R M, Emsley C L, Gao S, Sahota A, Hall K S, Farlow M R, Hendrie H

Abstract excerpt

A significant interaction among total serum cholesterol (TC), APOE genotype, and AD risk was found in a population-based study of elderly African Americans. Increasing TC was associated with increased AD risk in the group with no epsilon4 alleles, whereas TC was not associated with increased AD risk in the group with one or more epsilon4 alleles. Further study of the relationship between cholesterol and APOE...

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Source

Identifiers

PMID: 10636159
DOI: 10.1212/wnl.54.1.240

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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