Article
Apolipoprotein E polymorphism in elderly east Africans.
East African medical journal - 1 Oct 1997
Sayi J G, Patel N B, Premkumar D R, Adem A, Winblad B, Matuja W B, Mtui E P, Gatere S, Friedland R P, Koss E, Kalaria R N
Abstract excerpt
Current advances have shown the apolipoprotein E (APOE)-epsilon 4 allele to be highly associated with late-onset familial and sporadic Alzheimer's disease (AD) in Western populations. The association of APOE allele frequencies and dementia remain unknown in populations from developing countries. We recently initiated a project to examine APOE frequencies in non-demented and demented elderly East Africans. Blood...
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