Article
Apolipoprotein E polymorphism in elderly east Africans.
East African medical journal - 1 Oct 1997
Sayi J G, Patel N B, Premkumar D R, Adem A, Winblad B, Matuja W B, Mtui E P, Gatere S, Friedland R P, Koss E, Kalaria R N
Abstract excerpt
Current advances have shown the apolipoprotein E (APOE)-epsilon 4 allele to be highly associated with late-onset familial and sporadic Alzheimer's disease (AD) in Western populations. The association of APOE allele frequencies and dementia remain unknown in populations from developing countries....
Topics
- Aged
- Aged, 80 and over
- Alzheimer Disease
- Apolipoproteins E
- Case-Control Studies
- Gene Frequency
- Genotype
- Humans
- Kenya
- Mental Status Schedule
- Middle Aged
- Polymorphism, Genetic
- Tanzania