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Article

Apolipoprotein E and Alzheimer's disease: ethnic variation in genotypic risks.

Annals of neurology - 1 Feb 1995

Maestre G, Ottman R, Stern Y, Gurland B, Chun M, Tang M X, Shelanski M, Tycko B, Mayeux R

Abstract excerpt

The presence of the apolipoprotein epsilon 4 (apo epsilon 4) allele significantly increases the risk of Alzheimer's disease. Whether this is due to biological effects of the apo epsilon 4 protein or reflects linkage disequilibrium with an as yet unidentified Alzheimer's disease susceptibility gene is of critical importance. In a community study in northern Manhattan we found a fivefold increase in the risk of...

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PMID: 7847867
DOI: 10.1002/ana.410370217

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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