Apolipoprotein E and Alzheimer's disease: ethnic variation in genotypic risks.

doi:10.1002/ana.410370217

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Article

Apolipoprotein E and Alzheimer's disease: ethnic variation in genotypic risks.

Annals of neurology - 1 Feb 1995

Maestre G, Ottman R, Stern Y, Gurland B, Chun M, Tang M X, Shelanski M, Tycko B, Mayeux R

Abstract excerpt

The presence of the apolipoprotein epsilon 4 (apo epsilon 4) allele significantly increases the risk of Alzheimer's disease. Whether this is due to biological effects of the apo epsilon 4 protein or reflects linkage disequilibrium with an as yet unidentified Alzheimer's disease susceptibility gen...

Topics

Aged
Aged, 80 and over
Alleles
Alzheimer Disease
Apolipoproteins E
Black People
Case-Control Studies
Female
Genotype
Hispanic or Latino
Humans
Linkage Disequilibrium
Male
Middle Aged
Odds Ratio
White People
Black or African American

Source

Open in PubMed

Identifiers

PMID: 7847867
DOI: 10.1002/ana.410370217

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7847867-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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