Article
Relative risk of Alzheimer disease and age-at-onset distributions, based on APOE genotypes among elderly African Americans, Caucasians, and Hispanics in New York City.
American journal of human genetics - 1 Mar 1996
Tang M X, Maestre G, Tsai W Y, Liu X H, Feng L, Chung W Y, Chun M, Schofield P, Stern Y, Tycko B, Mayeux R
Abstract excerpt
Apolipoprotein-E epsilon 4 (APOE-epsilon 4) has been consistently associated with Alzheimer disease (AD) and may be responsible for an earlier age at onset. We have previously reported a diminished association between APOE-epsilon 4 and AD in African Americans. Using a new method, which allows inclusion of censored information, we compared relative risks by APOE genotypes in an expanded collection of cases and...
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