Article
Apolipoprotein E genotypes and Alzheimer's disease in a community study of elderly African Americans.
Annals of neurology - 1 Jan 1995
Hendrie H C, Hall K S, Hui S, Unverzagt F W, Yu C E, Lahiri D K, Sahota A, Farlow M, Musick B, Class C A
Abstract excerpt
As part of a community-based study of Alzheimer's disease (AD) in the African-American population age 65 and over, we have determined apolipoprotein E (Apo E) genotypes in 85 subjects (31 AD patients and 54 controls). The epsilon 4 allele of Apo E was strongly associated with AD in this populatio...
Topics
- Black or African American
- Aged
- Aged, 80 and over
- Alleles
- Alzheimer Disease
- Apolipoproteins E
- Black People
- DNA
- Female
- Gene Frequency
- Genotype
- Humans
- Incidence
- Indiana
- Logistic Models
- Male
- Nigeria
- Prevalence
