Article
Apolipoprotein E genotypes and Alzheimer's disease in a community study of elderly African Americans.
Annals of neurology - 1 Jan 1995
Hendrie H C, Hall K S, Hui S, Unverzagt F W, Yu C E, Lahiri D K, Sahota A, Farlow M, Musick B, Class C A
Abstract excerpt
As part of a community-based study of Alzheimer's disease (AD) in the African-American population age 65 and over, we have determined apolipoprotein E (Apo E) genotypes in 85 subjects (31 AD patients and 54 controls). The epsilon 4 allele of Apo E was strongly associated with AD in this population sample. The epsilon 4 allele frequency in AD patients was 40.3% compared with 13.9% in the control group, and 22.6%...
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