Article
Apolipoprotein E genotype, vascular risk and early cognitive impairment in an African Caribbean population.
Dementia and geriatric cognitive disorders - 1 Jan 2000
Stewart R, Russ C, Richards M, Brayne C, Lovestone S, Mann A
Abstract excerpt
A reduced risk of Alzheimer's disease (AD) associated with the apolipoprotein E (APOE) epsilon4 allele is reported in populations of African origin. In order to clarify possible reasons for this, we examined the association between APOE genotype and early cognitive impairment in a community-based African Caribbean UK population aged 55-75 years. APOE genotype was available for 202 participants, 57 (28%) of whom...
Topics
- Black or African American
- Age Factors
- Aged
- Alleles
- Alzheimer Disease
- Apolipoprotein E2
- Apolipoprotein E4
- Apolipoproteins E
- Arteriosclerosis
- Black People
- Caribbean Region