Article
Recombining sequence recombination in normal kappa-chain-expressing B cells.
Journal of immunology (Baltimore, Md. : 1950) - 1 Nov 1997
Dunda O, Corcos D
Abstract excerpt
Recombining sequence (RS) recombination is a DNA rearrangement that deletes one or two C kappa alleles in a large proportion of lambda-expressing B cells. Since its discovery, this recombination has been suggested to play a role in activating lambda gene rearrangements. A model involving a positive signal generated by RS recombination seems to be excluded, but another model that is still under consideration...
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