Article
The frequency of multiple recombination events occurring at the human Ig kappa L chain locus.
Journal of immunology (Baltimore, Md. : 1950) - 1 Feb 1990
Feddersen R M, Martin D J, Van Ness B G
Abstract excerpt
Products of Ig kappa L chain gene rearrangement in a variety of human B cell samples were investigated by sequential Southern blot hybridization analysis. By application of four region-specific probes (C kappa, J kappa, U' kappa and kappa de) a complete spectrum of kappa rearrangements, including both predicted and novel products, were detected. Nearly 30% of the products detected reflect multiple recombination...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
