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Article

Interallelic class switch recombination contributes significantly to class switching in mouse B cells.

Journal of immunology (Baltimore, Md. : 1950) - 15 May 2005

Reynaud Stéphane, Delpy Laurent, Fleury Laurence, Dougier Hei-Lanne, Sirac Christophe, Cogné Michel

Abstract excerpt

Except for the expression of IgM and IgD, DNA recombination is constantly needed for the expression of other Ig classes and subclasses. The predominant path of class switch recombination (CSR) is intrachromosomal, and the looping-out and deletion model has been abundantly documented. However, switch regions also occasionally constitute convenient substrates for interchromosomal recombination, since it is...

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Share to Gene Rearrangement, B-Lymphocyte, Heavy Chain
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Source

Identifiers

PMID: 15879114
DOI: 10.4049/jimmunol.174.10.6176

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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