Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mechanistic and selective constraints act on the establishment of V lambda J lambda junctions in the B cell repertoire.

Journal of immunology (Baltimore, Md. : 1950) - 1 Mar 1994

Boudinot P, Drapier A M, Cazenave P A, Sanchez P

Abstract excerpt

Only four different subtypes of lambda Ig chains have been described in the mouse: lambda 1, lambda 2(V2), lambda 2(Vx), and lambda 3. These chains are encoded by gene segments all sequenced and well localized in chromosome 16. Although the lambda Ig system is both simple and well characterized, no exhaustive analysis has been done concerning V lambda J lambda junctions in nonintentionally stimulated B cells. To...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Base Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cloning, Molecular

Share to DNA Primers

Share to Molecular Sequence Data

Share to Mutation

Share to Polymerase Chain Reaction

Source

Identifiers

PMID: 8133038

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mechanistic and selective constraints act on the establishment of V lambda J lambda junctions in the B cell repertoire.PMID 8133038Read ↗

An unusual type of V-J joining diversifies the primary repertoire of mouse lambda 1 light chains.Semantic proximity Read ↗

Distinct evolution at TCRα and TCRβ loci in the genus <i>Mus</i>Semantic proximity Read ↗

Non-canonical D1-D2 recombination produces two types of rearrangements and represents a conservative hidden stage of T-cell receptor beta chain generationSemantic proximity Read ↗

The mouse (Mus musculus) T cell receptor beta variable (TRBV), diversity (TRBD) and joining (TRBJ) genes.Semantic proximity Read ↗

Interallelic V(D)J trans-rearrangement within the beta T cell receptor gene is infrequent and occurs preferentially during attempted D beta to J beta joining.Semantic proximity Read ↗

Rearrangement of genetic information may produce immunoglobulin diversity.Semantic proximity Read ↗

Immunoglobulin Light Chain Gene Rearrangements, Receptor Editing and the Development of a Self-Tolerant Antibody RepertoireSemantic proximity Read ↗

Recombination signal sequences restrict chromosomal V(D)J recombination beyond the 12/23 rule.Semantic proximity Read ↗

Nomenclature and overview of the mouse (Mus musculus and Mus sp.) immunoglobulin kappa (IGK) genes.Semantic proximity Read ↗

MECHANISM AND CONTROL OF V(D)J RECOMBINATION AT THE IMMUNOGLOBULIN HEAVY CHAIN LOCUSSemantic proximity Read ↗

Molecular mechanisms and selective influences that shape the kappa gene repertoire of IgM+ B cells.Semantic proximity Read ↗

Molecular genetics at the T-cell receptor beta locus: insights into the regulation of V(D)J recombination.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.