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Article

Fibronectins are essential for heart and blood vessel morphogenesis but are dispensable for initial specification of precursor cells.

Blood - 15 Oct 1997

George E L, Baldwin H S, Hynes R O

Abstract excerpt

The underlying mechanisms of lethal cardiovascular defects associated with the fibronectin-null (FN.null) mutation in mouse embryos were investigated by lineage analysis of myocardial, endocardial, and endothelial cells. A wide variation in phenotype was observed on two genetic backgrounds. In the less severe class (C57/BL6 background), FN.null embryos display a defective heart. Myocardial cells express the...

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Source

Identifiers

PMID: 9376588

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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