Article
Myocardium and BMP signaling are required for endocardial differentiation.
Development (Cambridge, England) - 1 Jul 2015
Palencia-Desai Sharina, Rost Megan S, Schumacher Jennifer A, Ton Quynh V, Craig Michael P, Baltrunaite Kristina, Koenig Andrew L, Wang Jinhu, Poss Kenneth D, Chi Neil C, Stainier Didier Y R, Sumanas Saulius
Abstract excerpt
Endocardial and myocardial progenitors originate in distinct regions of the anterior lateral plate mesoderm and migrate to the midline where they coalesce to form the cardiac tube. Endocardial progenitors acquire a molecular identity distinct from other vascular endothelial cells and initiate expression of specific genes such as nfatc1. Yet the molecular pathways and tissue interactions involved in establishing...
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