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Article

Fibronectin and integrin alpha 5 play requisite roles in cardiac morphogenesis.

Developmental biology - 1 Sept 2013

Mittal Ashok, Pulina Maria, Hou Shuan-Yu, Astrof Sophie

Abstract excerpt

Fibronectin and its major receptor, integrin α5β1 are required for embryogenesis. These mutants have similar phenotypes, although, defects in integrin α5-deficient mice are milder. In this paper, we examined heart development in those mutants, in which the heart is formed, and discovered that both fibronectin and integrin α5 were required for cardiac morphogenesis, and in particular, for the formation of the...

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Identifiers

PMID: 23791818
DOI: 10.1016/j.ydbio.2013.06.010
PMCID: PMC3833817

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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