Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

In situ expression of PLP/DM-20, MBP, and CNP during embryonic and postnatal development of the jimpy mutant and of transgenic mice overexpressing PLP.

Journal of neuroscience research - 15 Oct 1997

Peyron F, Timsit S, Thomas J L, Kagawa T, Ikenaka K, Zalc B

Abstract excerpt

We analyzed by in situ hybridization the spatiotemporal expression of dm-20, myelin basic protein (MBP) and 2'-3' cyclic nucleotide phosphodiesterase (CNP) during embryonic and postnatal development of the normal mouse and two plp/dm-20 mutants: the jimpy mouse and a transgenic mouse overexpressing the plp gene. In the central nervous system (CNS) of the normal mouse, dm-20 mRNA was detected at embryonic day...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Newborn
Share to Embryonic and Fetal Development

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Transgenic

Share to Mutation

Share to Nerve Tissue Proteins

Share to Reference Values

Share to RNA, Messenger

Source

Identifiers

PMID: 9373029
DOI: 10.1002/(SICI)1097-4547(19971015)50:2<190::AID-JNR8>3.0.CO;2-A

Genes

CNP
MBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

In situ expression of PLP/DM-20, MBP, and CNP during embryonic and postnatal development of the jimpy mutant and of transgenic mice overexpressing PLP.PMID 9373029Read ↗

The early phenotype associated with the jimpy mutation of the proteolipid protein gene.Semantic proximity Read ↗

A combination of PLP and DM20 transgenes promotes partial myelination in the jimpy mouse.Semantic proximity Read ↗

Separate proteolipid protein/DM20 enhancers serve different lineages and stages of development.Semantic proximity Read ↗

Transgenic and natural mouse models of proteolipid protein (PLP)-related dysmyelination and demyelination.Semantic proximity Read ↗

Epigenetic factors up-regulate expression of myelin proteins in the dysmyelinating jimpy mutant mouse.Semantic proximity Read ↗

Temperature-dependent regulation of PLP/DM20 and CNP gene expression in two conditionally-immortalized jimpy oligodendrocyte cell lines.Semantic proximity Read ↗

Rumpshaker-like proteolipid protein (PLP) ratio in a mouse model with unperturbed structural and functional integrity of the myelin sheath and axons in the central nervous system.Semantic proximity Read ↗

Novel isoforms of mouse myelin basic protein predominantly expressed in embryonic stage.Semantic proximity Read ↗

Widespread expression of the peripheral myelin protein‐22 gene (<i>pmp</i>22) in neural and non‐neural tissues during murine developmentSemantic proximity Read ↗

Mutations in the myelin proteolipid protein gene alter oligodendrocyte gene expression in jimpy and jimpymsd mice.Semantic proximity Read ↗

Developmental expression of major myelin protein genes in the CNS of X-linked hypomyelinating mutant rumpshaker.Semantic proximity Read ↗

Normal temporal and spatial distribution of oligodendrocyte progenitors in the myelin-deficient (md) rat.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.