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Article

Normal temporal and spatial distribution of oligodendrocyte progenitors in the myelin-deficient (md) rat.

Journal of neuroscience research - 1 Feb 1997

Pringle N P, Nadon N L, Rhode D M, Richardson W D, Duncan I D

Abstract excerpt

A point mutation in exon 3 of the proteolipid protein (PLP) gene of the myelin-deficient (md) rat leads to a failure of oligodendrocyte maturation and early death of oligodendrocytes, resulting in dysmyelination. It has been suggested that an alternative-splice isoform of PLP, known as DM-20, might be expressed in oligodendrocyte progenitors in the embryonic central nervous system (CNS), raising the possibility...

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PMID: 9039648
DOI: 10.1002/(sici)1097-4547(19970201)47:3<264::aid-jnr4>3.0.co;2-g

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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