Epigenetic factors up-regulate expression of myelin proteins in the dysmyelinating jimpy mutant mouse.

doi:10.1002/(SICI)1097-4695(199602)29:2<138::AID-NEU2>3.0.CO;2-B

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Article

Epigenetic factors up-regulate expression of myelin proteins in the dysmyelinating jimpy mutant mouse.

Journal of neurobiology - 1 Feb 1996

Knapp P E, Benjamins J A, Skoff R P

Abstract excerpt

Proteolipid protein (PLP) is a major structural component of central nervous system (CNS) myelin. Evidence exists that PLP or the related splice variant DM-20 protein may also play a role in early development of oligodendrocytes (OLs), the cells that form CNS myelin. There are several naturally o...

Topics

Animals
Cell Death
Cells, Cultured
Demyelinating Diseases
Female
Glycolipids
Immunohistochemistry
Lipoproteins
Male
Mice
Mice, Jimpy
Mutation
Myelin Basic Protein
Myelin Proteins
Oligodendroglia
Phenotype
Protein Biosynthesis
Rats

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