Article
Developmental expression of major myelin protein genes in the CNS of X-linked hypomyelinating mutant rumpshaker.
Journal of neuroscience research - 1 Oct 1992
Mitchell L S, Gillespie S C, McAllister F, Fanarraga M L, Kirkham D, Kelly B, Brophy P J, Griffiths I R, Montague P, Kennedy P G
Abstract excerpt
Rumpshaker (rsh) is an X-linked mutation causing hypomyelination of the CNS of mice and has recently been identified as an allele of jimpy (jp). The mutation (known as jprsh) differs in several respects from other X-linked myelin mutants, including jp, in that mice have normal longevity, oligoden...
Topics
- Aging
- Alleles
- Animals
- Blotting, Northern
- Brain
- Demyelinating Diseases
- Gene Expression Regulation
- Immunoblotting
- Immunohistochemistry
- In Situ Hybridization
- Mice
- Mice, Mutant Strains
- Myelin Basic Protein
- Myelin Proteins
- Protein Biosynthesis