Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotype of transgenic mice overexpressing GLUT4 and hexokinase II in muscle.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Nov 1997

Lombardi A M, Moller D, Loizeau M, Girard J, Leturque A

Abstract excerpt

To optimize glucose utilization, double transgenic mice were created by crossing mice overexpressing glucose transporter GLUT4 with mice overexpressing hexokinase (HKII) in muscle. Transgenic mice overexpressing GLUT4 alone have exhibited improvements in glucose tolerance and insulin action. In v...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain
Share to Crosses, Genetic
Share to Exons

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Insulin

Share to Isoenzymes

Share to Mice, Inbred Strains

Share to Mice, Transgenic

Source

Identifiers

PMID: 9367348
DOI: 10.1096/fasebj.11.13.9367348

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-9367348-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotype of transgenic mice overexpressing GLUT4 and hexokinase II in muscle.PMID 9367348Read ↗

Peripheral but not hepatic insulin resistance in mice with one disrupted allele of the glucose transporter type 4 (GLUT4) gene.Semantic proximity Read ↗

Control of exercise-stimulated muscle glucose uptake by GLUT4 is dependent on glucose phosphorylation capacity in the conscious mouse.Semantic proximity Read ↗

K(ATP) channel knockout mice crossbred with transgenic mice expressing a dominant-negative form of human insulin receptor have glucose intolerance but not diabetes.Semantic proximity Read ↗

Diet-induced loss of adipose Hexokinase 2 triggers hyperglycemiaSemantic proximity Read ↗

Glucokinase gene locus transgenic mice are resistant to the development of obesity-induced type 2 diabetes.Semantic proximity Read ↗

Transgenic knockouts reveal a critical requirement for pancreatic beta cell glucokinase in maintaining glucose homeostasis.Semantic proximity Read ↗

Conditional, tissue-specific expression of Q205L G alpha i2 in vivo mimics insulin action.Semantic proximity Read ↗

Both isoforms of ketohexokinase are dispensable for normal growth and developmentSemantic proximity Read ↗

Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase.Semantic proximity Read ↗

Effects of increased glucokinase gene copy number on glucose homeostasis and hepatic glucose metabolism.Semantic proximity Read ↗

Development of glucose intolerance in male transgenic mice overexpressing human glycogen synthase kinase-3beta on a muscle-specific promoter.Semantic proximity Read ↗

Abnormal regulation of HGP by hyperglycemia in mice with a disrupted glucokinase allele.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.