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Article

Effects of increased glucokinase gene copy number on glucose homeostasis and hepatic glucose metabolism.

The Journal of biological chemistry - 5 Sept 1997

Niswender K D, Shiota M, Postic C, Cherrington A D, Magnuson M A

Abstract excerpt

The relationship between glucokinase (GK) gene copy number and glucose homeostasis was studied in transgenic mice with additional copies of the entire GK gene locus (Niswender, K. D., Postic, C., Jetton, T. L., Bennett, B. D., Piston, D. W., Efrat, S., and Magnuson, M. A. (1997) J. Biol. Chem. 272, 22564-22569). The plasma glucose concentration was reduced by 25 +/- 3% and 37 +/- 4% in mice with one or two extra...

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Identifiers

PMID: 9278411
DOI: 10.1074/jbc.272.36.22570

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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