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Article

Induction of CYP2D6 in pregnancy.

Clinical pharmacology and therapeutics - 1 Oct 1997

Wadelius M, Darj E, Frenne G, Rane A

Abstract excerpt

Expression of the drug-metabolizing enzyme cytochrome P4502D6 (CYP2D6) is predominantly under genetic control, and enzyme-inducing drugs have little influence on its activity. We studied the activity of CYP2D6 during pregnancy. One hundred forty pregnant women were genotyped for CYP2D6. Seventeen of them (four poor metabolizers, seven heterozygous extensive metabolizers, and six extensive metabolizers) were...

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Source

Identifiers

PMID: 9357391
DOI: 10.1016/S0009-9236(97)90118-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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