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Article

Transcriptional Regulation of CYP2D6 Expression.

Drug metabolism and disposition: the biological fate of chemicals - 1 Jan 2017

Pan Xian, Ning Miaoran, Jeong Hyunyoung

Abstract excerpt

CYP2D6-mediated drug metabolism exhibits large interindividual variability. Although genetic variations in the CYP2D6 gene are well known contributors to the variability, the sources of CYP2D6 variability in individuals of the same genotype remain unexplained. Accumulating data indicate that transcriptional regulation of CYP2D6 may account for part of CYP2D6 variability. Yet, our understanding of factors...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27698228
DOI: 10.1124/dmd.116.072249
PMCID: PMC5193069

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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