Article
Determination of p-aminosalicylic acid and its N-acetylated metabolite in human urine by capillary zone electrophoresis as a measure of in vivo N-acetyltransferase 1 activity.
Journal of chromatography. B, Biomedical sciences and applications - 12 Sept 1997
Cummins C L, O'Neil W M, Soo E C, Lloyd D K, Wainer I W
Abstract excerpt
A capillary zone electrophoresis method has been developed for the determination of p-aminosalicylic acid (PAS) and its metabolite, N-acetyl-p-aminosalicylic acid (N-acetyl-PAS), in urine. A linear relationship was observed between time-normalized peak area and the concentration of the parent and...
Topics
- Acetamides
- Adolescent
- Adult
- Aminosalicylic Acid
- Aminosalicylic Acids
- Arylamine N-Acetyltransferase
- Electrophoresis, Capillary
- Female
- Humans
- Male
- Middle Aged
- Phenotype
- Salicylates