Article
A competitive enzyme linked immunosorbent assay for the determination of N-acetyltransferase (NAT2) phenotypes.
Journal of pharmaceutical and biomedical analysis - 1 Aug 1995
Wong P, Leyland-Jones B, Wainer I W
Abstract excerpt
The ratio of 5-acetylamino-6-amino-3-methyluracil (AAMU) to 1-methylxanthine (1X) in urine samples after caffeine ingestion can be used to indicate human N-acetyltransferase (NAT2) phenotypes. In previous studies, this ratio has been determined by LC or capillary electrophoresis. The possibility...
Topics
- Animals
- Antibody Formation
- Antigen-Antibody Complex
- Arylamine N-Acetyltransferase
- Binding, Competitive
- Cross Reactions
- Enzyme-Linked Immunosorbent Assay
- Female
- Humans
- Immunoglobulin G
- Magnetic Resonance Spectroscopy
- Phenotype
- Rabbits
- Uracil
- Xanthines
