Validity of saliva samples for the estimation of dipyrone metabolites pharmacokinetics.

Article

Validity of saliva samples for the estimation of dipyrone metabolites pharmacokinetics.

Arzneimittel-Forschung - 1 Nov 1993

Caraco Y, Zylber-Katz E, Granit L, Levy M

Abstract excerpt

Plasma and saliva pharmacokinetics of dipyrone (CAS 5907-38-0) metabolites, 4-methylaminoantipyrine (MAA), 4-aminoantipyrine (AA), 4-formylaminoantipyrine (FAA) and 4-acetylaminoantipyrine (AAA), has been studied in 10 healthy volunteers, after oral administration of 1.0 g dipyrone, MAA, AA, FAA...

Topics

Acetylation
Adult
Aminopyrine
Ampyrone
Dipyrone
Female
Half-Life
Humans
Male
Phenotype
Pyrazolones
Saliva

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.