Article
A linkage study across the T cell receptor A and T cell receptor B loci in families with rheumatoid arthritis.
Arthritis and rheumatism - 1 Oct 1997
Hall F C, Brown M A, Weeks D E, Walsh S, Nicod A, Butcher S, Andrews L J, Wordsworth B P
Abstract excerpt
OBJECTIVE: To examine whether the T cell receptor (TCR) A or TCRB loci exhibit linkage with disease in multiplex rheumatoid arthritis (RA) families. METHODS: A linkage study was performed in 184 RA families from the UK Arthritis and Rheumatism Council Repository, each containing at least 1 affected sibpair. The microsatellites D14S50, TCRA, and D14S64 spanning the TCRA locus and D7S509, Vbeta6.7, and D7S688...
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