Article
Dense genome-wide linkage analysis of rheumatoid arthritis, including covariates.
Arthritis and rheumatism - 1 Sept 2004
Osorio Y Fortéa José, Bukulmez Hulya, Petit-Teixeira Elisabeth, Michou Laétitia, Pierlot Céline, Cailleau-Moindrault Séverine, Lemaire Isabelle, Lasbleiz Sandra, Alibert Olivier, Quillet Patrick, Bardin Thomas, Prum Bernard, Olson Jane M, Cornélis François
Abstract excerpt
OBJECTIVE: Rheumatoid arthritis (RA) is a heterogeneous disease that exhibits a complex genetic component. Previous RA genome scans confirmed the involvement of the HLA region and generated data on suggestive signals at non-HLA regions, albeit with few overlaps in findings between studies. The present study was undertaken to detect potential RA gene regions and to estimate the number of true RA gene regions,...
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