Article
Mapping of a novel susceptibility gene for rheumatoid arthritis in the telomeric MHC region.
Cytokine - 21 Oct 2005
Kilding Rachael, Wilson Anthony G
Abstract excerpt
Rheumatoid arthritis (RA) is a complex heterogeneous disease with an estimated genetic contribution to of 30-50%. Approximately one third arises from the major histocompatibility complex (MHC) at 6p21.3. The contribution of specific DRB1 alleles encoding the shared epitope has been well described, however, several recent studies have suggested that additional telomeric genetic influences may exist. This region is...
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