Article
Linkage and association analysis of candidate genes in rheumatoid arthritis.
The Journal of rheumatology - 1 Aug 2001
John S, Eyre S, Myerscough A, Barrett J, Silman A, Ollier W, Worthington J
Abstract excerpt
OBJECTIVES: To test for linkage and association to rheumatoid arthritis (RA) in multiplex families for polymorphic markers in candidate gene loci. Loci including the cytokine cluster on 5q31.1 and IL10, both previously investigated in RA, were included along with several other genes including ICAM-1, cMYC, the cytokine cluster on 17q11.2 and IL1RA. METHODS: One hundred eighty-five multiplex RA families were...
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