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Article

Rapamycin specifically interferes with the developmental response of fission yeast to starvation.

Journal of bacteriology - 1 Oct 1997

Weisman R, Choder M, Koltin Y

Abstract excerpt

Rapamycin is a microbial macrolide which belongs to a family of immunosuppressive drugs that suppress the immune system by blocking stages of signal transduction in T lymphocytes. In Saccharomyces cerevisiae cells, as in T lymphocytes, rapamycin inhibits growth and cells become arrested at the G1 stage of the cell cycle. Rapamycin is also an effective antifungal agent, affecting the growth of yeast and...

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Identifiers

PMID: 9335279
DOI: 10.1128/jb.179.20.6325-6334.1997
PMCID: PMC179546

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Rapamycin specifically interferes with the developmental response of fission yeast to starvation.PMID 9335279Read ↗

Targets for cell cycle arrest by the immunosuppressant rapamycin in yeast.Semantic proximity Read ↗

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Loss of the TOR kinase Tor2 mimics nitrogen starvation and activates the sexual development pathway in fission yeast.Semantic proximity Read ↗

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Regulation of leucine uptake by tor1+ in Schizosaccharomyces pombe is sensitive to rapamycin.Semantic proximity Read ↗

Target of rapamycin (TOR): balancing the opposing forces of protein synthesis and degradation.Semantic proximity Read ↗

The yeast Tor signaling pathway is involved in G2/M transition via polo-kinase.Semantic proximity Read ↗

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