Article
Requirement of Saccharomyces cerevisiae Ras for completion of mitosis.
Science (New York, N.Y.) - 17 Nov 1995
Morishita T, Mitsuzawa H, Nakafuku M, Nakamura S, Hattori S, Anraku Y
Abstract excerpt
In the yeast Saccharomyces cerevisiae, Ras regulates adenylate cyclase, which is essential for progression through the G1 phase of the cell cycle. However, even when the adenosine 3',5'-monophosphate (cAMP) pathway was bypassed, the double disruption of RAS1 and RAS2 resulted in defects in growth at both low and high temperatures. Furthermore, the simultaneous disruption of RAS1, RAS2, and the RAS-related gene...
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