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Article

The yeast Tor signaling pathway is involved in G2/M transition via polo-kinase.

PloS one - 21 May 2008

Nakashima Akio, Maruki Yoshiko, Imamura Yuko, Kondo Chika, Kawamata Tomoko, Kawanishi Ippei, Takata Hideki, Matsuura Akira, Lee Kyung S, Kikkawa Ushio, Ohsumi Yoshinori, Yonezawa Kazuyoshi, Kamada Yoshiaki

Abstract excerpt

The target of rapamycin (Tor) protein plays central roles in cell growth. Rapamycin inhibits cell growth and promotes cell cycle arrest at G1 (G0). However, little is known about whether Tor is involved in other stages of the cell division cycle. Here we report that the rapamycin-sensitive Tor complex 1 (TORC1) is involved in G2/M transition in S. cerevisiae. Strains carrying a temperature-sensitive allele of...

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Identifiers

PMID: 18493323
DOI: 10.1371/journal.pone.0002223
PMCID: PMC2375053

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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