Article
Tor and cyclic AMP-protein kinase A: two parallel pathways regulating expression of genes required for cell growth.
Eukaryotic cell - 1 Jan 2005
Zurita-Martinez Sara A, Cardenas Maria E
Abstract excerpt
In the budding yeast Saccharomyces cerevisiae, the Tor and cyclic AMP-protein kinase A (cAMP-PKA) signaling cascades respond to nutrients and regulate coordinately the expression of genes required for cell growth, including ribosomal protein (RP) and stress-responsive (STRE) genes. The inhibition of Tor signaling by rapamycin results in repression of the RP genes and induction of the STRE genes. Mutations that...
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