Article
Absence of angiotensin II type 1 receptor gene mutations in human adrenal tumors.
European journal of endocrinology - 1 Sept 1997
Sachse R, Shao X J, Rico A, Finckh U, Rolfs A, Reincke M, Hensen J
Abstract excerpt
Regulatory actions of angiotensin II (AngII), which is involved in the pathophysiology of hypertension and also participates in cell proliferation and cell differentiation, are mainly mediated by AngII type 1 (AT1) receptor. Recently, activating mutations of receptors causing hyperfunctioning endocrine diseases have been described in the case of the TSH and LH receptors, implicating that such mutations might...
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