Article
PCR-SSCP analysis of the angiotensin II type 1 receptor gene in patients with aldosterone-producing adenomas.
Clinical and experimental pharmacology & physiology - 1 Jan 2000
Klemm S A, Ballantine D M, Tunny T J, Stowasser M, Gordon R D
Abstract excerpt
1. In patients with primary aldosteronism due to angiotensin-responsive and angiotensin-unresponsive aldosterone-producing adenomas, no differences in the coding region of the angiotensin II type 1 (AT1) receptor gene were observed compared to normal subjects in peripheral blood leucocyte DNA. 2....
Topics
- Adenoma
- Adrenal Gland Neoplasms
- Adult
- Aged
- Aldosterone
- Alleles
- Autoradiography
- Chi-Square Distribution
- DNA
- Electrophoresis, Polyacrylamide Gel
- Female
- Gene Frequency
- Humans
- Hyperaldosteronism
- Male
- Middle Aged
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length