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Article

Somatic mutations of the angiotensin II (AT1) receptor gene are not present in aldosterone-producing adenoma.

The Journal of clinical endocrinology and metabolism - 1 Feb 1997

Davies E, Bonnardeaux A, Plouin P F, Corvol P, Clauser E

Abstract excerpt

Angiotensin II stimulates aldosterone secretion from the adrenal zona glomerulosa and mediates most of its biological effects via G protein-coupled type 1 angiotensin II receptors (AT1). A number of G protein-coupled receptors are constitutively activated as a result of somatic mutations in the gene encoding the protein. It is, therefore, possible that primary hyperaldosteronism caused by an aldosterone-producing...

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Identifiers

PMID: 9024263
DOI: 10.1210/jcem.82.2.3764

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Somatic mutations of the angiotensin II (AT1) receptor gene are not present in aldosterone-producing adenoma.PMID 9024263Read ↗

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Somatic mutations of the ATP1A1 gene and aldosterone-producing adenomas.Semantic proximity Read ↗

Mutations in CYP11B1 gene converting 11beta-hydroxylase into an aldosterone-producing enzyme are not present in aldosterone-producing adenomas.Semantic proximity Read ↗

Absence of somatic mutations in natriuretic peptide receptor type A gene in human aldosterone-secreting adenomas.Semantic proximity Read ↗

Aldosterone-Regulating Receptors and Aldosterone-Driver Somatic Mutations.Semantic proximity Read ↗

PCR-SSCP analysis of the angiotensin II type 1 receptor gene in patients with aldosterone-producing adenomas.Semantic proximity Read ↗

Prevalence and clinical correlates of somatic mutation in aldosterone producing adenoma-Taiwanese population.Semantic proximity Read ↗

A Meta-Analysis of Somatic KCNJ5 K(+) Channel Mutations In 1636 Patients With an Aldosterone-Producing Adenoma.Semantic proximity Read ↗

[Structure and functions of the angiotensin II AT1 receptors during evolution].Semantic proximity Read ↗

Novel Insertion Mutation in KCNJ5 Channel Produces Constitutive Aldosterone Release From H295R Cells.Semantic proximity Read ↗

Angiotensin II receptors: protein and gene structures, expression and potential pathological involvements.Semantic proximity Read ↗

Association of restriction fragment length polymorphism at the atrial natriuretic peptide gene locus with aldosterone responsiveness to angiotensin in aldosterone-producing adenoma.Semantic proximity Read ↗

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