Article
[Structure and functions of the angiotensin II AT1 receptors during evolution].
Journal de la Societe de biologie - 1 Jan 2009
Auzan Colette, Clauser Eric
Abstract excerpt
Angiotensin II AT1 receptor is a G protein coupled receptor, which transduces the physiological effects (vasoconstriction, aldosterone secretion) f this vasoactive peptide. On an evolutionary point of view, this receptor has appeared early in the development of vertebrates, since it is present in cartilagenous fish. It has been duplicated in rodents without any consequence on its functions. It is unlikely that...
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